Pheochromocytoma. Cause of Secondary Hypertension in von Recklinghausen\u2019s Disease.<\/strong><\/h2>\n[\/et_pb_text][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n
Abstract<\/h3>\n
Pheochromocytoma is a tumor that arises from chromaffin cells of the sympathetic nervous system, which produces, stores, metabolizes, and releases catecholamines and their metabolites. About 80\u201385 % is located in the adrenal medulla, while the remaining 10\u201315 % originates from extra-adrenal chromaffin tissue and is referred to as paragangliomas.<\/p>\n
These tumors share clinical characteristics; therefore, the diagnostic approach is similar.<\/p>\n
They are an uncommon cause of secondary hypertension, with a prevalence ranging from 0.1\u20131 %. They may be sporadic or associated with genetic disorders such as multiple endocrine neoplasia type 2, von Hippel\u2013Lindau disease, familial paraganglioma, and neurofibromatosis type 1 or von Recklinghausen\u2019s disease, appearing in the latter in 1\u20135 % of patients at a mean age of 42 years, although the range is variable.
The diagnostic suspicion should be based on clinical findings and confirmed through biochemical testing of plasma and\/or urinary metanephrines, as well as anatomical tumor identification by computed tomography or magnetic resonance imaging.<\/p>\n
The treatment of choice is laparoscopic surgery, following medical preparation with alpha-adrenergic blockade.
The prognosis is usually good, although around 10 % of pheochromocytomas and 50 % of paragangliomas are malignant, and the 5-year survival rate in these patients is less than 50 %.
We present the clinical case of a 19-year-old patient with a history of neurofibromatosis type I who was diagnosed with a left-sided pheochromocytoma, for which surgical treatment was indicated.
In conclusion, this clinical case highlights the importance of suspecting secondary causes of arterial hypertension in young patients, such as pheochromocytoma, a rare tumor with a wide range of nonspecific symptoms, and its association with genetic diseases. It also emphasizes the relevance of individualized management by a multidisciplinary team.<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb min_height=\u00bb72.6px\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n
Keywords<\/h3>\n
Pheochromocytoma, secondary arterial hypertension, von Recklinghausen\u00b4s disease, neurofibromatosis<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n
Introducci\u00f3n<\/h3>\n
El t\u00e9rmino feocromocitoma (FEO) proviene del griego: \u00abPhios\u00bb significa oscuro, \u00abchromo\u00bb significa color y \u00abcytoma\u00bb, tumor. Se refiere al color que adquieren las c\u00e9lulas cuando se ti\u00f1en en las sales de cromo.
Es un tumor raro, productor de catecolaminas originado en la m\u00e9dula suprarrenal, con una incidencia anual de 1-2 cada 100 000 habitantes. Su prevalencia es entre 0,1-1 % de los hipertensos, con un pico desde la pubertad hasta los 40 a\u00f1os.1<\/sup> El 85 % son tumores espor\u00e1dicos y \u00fanicos; mientras que el 15-25 % restante se asocia a s\u00edndromes gen\u00e9ticos hereditarios autos\u00f3mico dominante.2<\/sup><\/p>\nLa neurofibromatosis tipo 1 (NF-1) o enfermedad de von Recklinhousen es uno de los s\u00edndromes cl\u00e1sicamente asociados al feo, siendo Suzuki, en 1910, quien reconoci\u00f3 por primera vez la asociaci\u00f3n.
Se trata de una enfermedad multisist\u00e9mica, de herencia autos\u00f3mica dominante, que afecta principalmente la piel y sistema nervioso, con expresividad cl\u00ednica variable. Su diagn\u00f3stico es cl\u00ednico. Entre las m\u00faltiples manifestaciones de la NF-1, el FEO aparece en el 1-5 % de los pacientes. La mayor\u00eda lo desarrolla en la edad adulta con una edad media de 42 a\u00f1os, con rango variable, siendo la hipertensi\u00f3n arterial su principal s\u00edntoma. La localizaci\u00f3n es en general adrenal unifocal (10-20 % multifocales; 6 % extraadrenales, 12 % malignos).\u00a03<\/sup>
El rango de mutaciones detectadas en estos pacientes es amplio y no se reconoce una mutaci\u00f3n espec\u00edfica que favorezca a su desarrollo. El diagn\u00f3stico tanto con pruebas bioqu\u00edmicas como de
imagen no difiere en comparaci\u00f3n con el FEO espor\u00e1dico. Suelen ser secretores predominantemente de adrenalina y presentar cifras elevadas de metanefrinas y normetanefrinas en plasma y orina.
El tratamiento de elecci\u00f3n es quir\u00fargico, laparosc\u00f3pico, tras previa preparaci\u00f3n con alfa bloqueantes.
No se recomienda el cribado bioqu\u00edmico de esta patolog\u00eda en pacientes con NF-1 dado su baja frecuencia.<\/p>\n[\/et_pb_text][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n
Objetivos<\/h3>\n\n- Sospechar hipertensi\u00f3n secundaria en pacientes j\u00f3venes con crisis hipertensivas.<\/li>\n
- Resaltar la asociaci\u00f3n del feocromocitoma con s\u00edndromes gen\u00e9ticos en las l\u00edneas germinales.<\/li>\n
- Sospechar, confirmar y localizar son los tres pasos fundamentales para un adecuado abordaje.<\/li>\n
- Analizar la importancia de un adecuado tratamiento y preparaci\u00f3n prequir\u00fargica.<\/li>\n<\/ol>\n
[\/et_pb_text][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n
Presentaci\u00f3n del caso<\/h3>\n
Paciente masculino de 19 a\u00f1os, ex tabaquista reciente, sin antecedentes cardiovasculares relevantes, con diagn\u00f3stico de neurofibromatosis tipo 1 e historial de resecci\u00f3n de neurofibroma cervical. Consulta en guardia por amaurosis del ojo izquierdo de una semana de evoluci\u00f3n. Al examen f\u00edsico se encontraba estable hemodin\u00e1micamente, afebril, hipertenso (tensi\u00f3n arterial 210\/110 mmHg) y taquic\u00e1rdico (120 lpm). Fue evaluado por neurolog\u00eda, quienes solicitaron resonancia magn\u00e9tica de cr\u00e1neo y \u00f3rbita, sin hallazgos expansivos ni vasculares. Se evidenci\u00f3 alteraci\u00f3n de se\u00f1al en el polo posterior del globo ocular derecho, compatible con probable degradaci\u00f3n hem\u00e1tica; y ante la sospecha de neuritis \u00f3ptica indicaron pulsos de corticoides.
Adem\u00e1s se solicit\u00f3 fondo de ojo que mostr\u00f3 papilas con bordes difusos, exudados y hemorragias en los cuatro cuadrantes, con desprendimiento exudativo macular derecho (Figura 1).
Se realiz\u00f3 electrocardiograma (ECG) con signos de hipertrofia ventricular izquierda (Sokolow 45 mm) (Figura 2), y ecocardiograma que mostr\u00f3 hipertrofia mioc\u00e1rdica conc\u00e9ntrica leve (masa de ventr\u00edculo izquierdo indexada 124 g\/m2<\/sup>). Por la edad, la severidad del cuadro y el da\u00f1o de \u00f3rgano blanco, se sospech\u00f3 hipertensi\u00f3n secundaria. Como ex\u00e1menes adicionales para la b\u00fasqueda etiol\u00f3gica se solicitaron: ecograf\u00eda Doppler renal que fue normal; tomograf\u00eda y resonancia abdominal que revelaron una masa suprarrenal izquierda de 48\u00d738 mm, con caracter\u00edsticas imagenol\u00f3gicas compatibles con feocromocitoma (Figura 3). Para la confirmaci\u00f3n diagn\u00f3stica se evaluaron las metanefrinas urinarias y catecolaminas plasm\u00e1ticas que resultaron elevadas (Tabla 1). Se inici\u00f3 preparaci\u00f3n prequir\u00fargica con hidrataci\u00f3n y tratamiento antihipertensivo con calcio, antagonistas y alfabloqueantes, y se realiz\u00f3 adrenalectom\u00eda videolaparosc\u00f3pica izquierda (Figura 4). El paciente evolucion\u00f3 favorablemente, con mejor\u00eda del control tensional. El an\u00e1lisis anatomopatol\u00f3gico confirm\u00f3 feocromocitoma.<\/p>\n[\/et_pb_text][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n
Discusi\u00f3n<\/h3>\n
La neurofibromatosis tipo 1 (NF1) es una enfermedad neurocut\u00e1nea progresiva, de herencia autos\u00f3mica dominante, con una incidencia de 1:3000.4<\/sup> La mitad de los casos son gen\u00e9ticos y el resto se debe a mutaciones de novo en el gen que codifica la neurofibromina. Nuestro paciente, con antecedente de neurofibromas cut\u00e1neos y m\u00faltiples manchas caf\u00e9 con leche (Figura 5), cumpl\u00eda con los criterios cl\u00ednicos diagn\u00f3sticos de NF1.5<\/sup>
La hipertensi\u00f3n arterial (HTA) es una condici\u00f3n cr\u00f3nica de etiolog\u00eda multifactorial y controlable, definida por cifras superiores a 140\/90 mmHg. La evaluaci\u00f3n de HTA en pacientes j\u00f3venes requiere investigar etiolog\u00edas secundarias, presentes en aproximadamente el 5-10 % de los casos.2<\/sup> La sospecha cl\u00ednica aumenta ante la instauraci\u00f3n precoz de HTA, inicio s\u00fabito, o hallazgos en estudios complementarios que sugieran causas secundarias espec\u00edficas. En el contexto de nuestro paciente, la presencia de antecedentes de NF1 y una masa adrenal gener\u00f3 la sospecha de un feocromocitoma (FEO), el cual se presenta entre 0,1-5 % de los casos.
La sospecha cl\u00ednica se confirm\u00f3 bioqu\u00edmicamente con niveles elevados de metanefrinas y catecolaminas fraccionadas plasm\u00e1ticas y urinarias, arrojando valores 3 veces superiores al l\u00edmite superior normal.6<\/sup> Las im\u00e1genes de tomograf\u00eda computada y resonancia magn\u00e9tica de abdomen mostraron una masa de paredes gruesas, centro hipodenso, hiperintensa en T2, con realce tras contraste, compatibles con feocromocitoma.
El tratamiento de elecci\u00f3n en estos casos es la resecci\u00f3n quir\u00fargica, preferentemente mediante adrenalectom\u00eda videolaparosc\u00f3pica, salvo que exista invasi\u00f3n a tejidos circundantes. La preparaci\u00f3n
preoperatoria con bloqueo alfa-adren\u00e9rgico y antagonistas c\u00e1lcicos, adem\u00e1s de una adecuada hidrataci\u00f3n parenteral, son fundamentales para reducir el riesgo de crisis hipertensivas intraoperatorias y disminuir la mortalidad, la cual se ha reducido a menos del 5 % en centros especializados.7<\/sup><\/p>\n[\/et_pb_text][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n
Conclusiones<\/h3>\n
La hipertensi\u00f3n arterial es uno de los principales factores de riesgo cardiovascular, con alta prevalencia en la poblaci\u00f3n general y una importante carga de morbimortalidad. En pacientes j\u00f3venes, especialmente menores de 40 a\u00f1os, con inicio s\u00fabito de la enfermedad y signos de da\u00f1o en \u00f3rgano blanco, resulta fundamental considerar formas secundarias de hipertensi\u00f3n. La detecci\u00f3n precoz de estas etiolog\u00edas permite instaurar un tratamiento espec\u00edfico y oportuno, que en algunos casos puede conducir a la curaci\u00f3n, y en otros, a un mejor control de la enfermedad y mejora en la calidad de vida. Contamos con diversas herramientas diagn\u00f3sticas para ello, pero la clave inicial radica en una adecuada sospecha cl\u00ednica, sustentada en una anamnesis detallada y un examen f\u00edsico exhaustivo.<\/p>\n
[\/et_pb_text][et_pb_text _builder_version=\u00bb4.16″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n
Conflicto de intereses<\/h3>\n
Los autores declaran no tener conflicto de intereses.<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00bb1″ admin_label=\u00bbTablas\u00bb _builder_version=\u00bb4.16″ custom_padding=\u00bb1px|0px|62px|0px|false|false\u00bb locked=\u00bboff\u00bb collapsed=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_row custom_padding_last_edited=\u00bbon|phone\u00bb _builder_version=\u00bb4.16″ background_color=\u00bb#ffffff\u00bb max_width=\u00bb1280px\u00bb custom_padding=\u00bb12px|40px|12px|40px|true|false\u00bb custom_padding_tablet=\u00bb\u00bb custom_padding_phone=\u00bb|20px||20px||true\u00bb animation_style=\u00bbzoom\u00bb animation_intensity_zoom=\u00bb2%\u00bb border_radii=\u00bbon|12px|12px|12px|12px\u00bb box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb50px\u00bb box_shadow_blur=\u00bb80px\u00bb box_shadow_color=\u00bbrgba(15,19,25,0.1)\u00bb use_custom_width=\u00bbon\u00bb custom_width_px=\u00bb1280px\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.16″ custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n
<\/strong><\/p>\nTablas<\/strong><\/h3>\nTabla 1: Resultados de laboratorio<\/strong><\/p>\n[\/et_pb_text][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n
\n\n\n| \n Metanefrinas y normetanefrinas urinarias (Orina 24 h)<\/p>\n<\/td>\n | \n – Metanefrina: 374 (VR: 44-261 ug\/24 h)
– Normetanefrina: 516 (VR: 103-521 ug\/24 h)<\/p>\n<\/td>\n<\/tr>\n |
\n| \n Adrenalina plasm\u00e1tica<\/p>\n<\/td>\n | \n 85 (VR: Supino 10-100 pg\/ml\/ de pie: 20-140 pg\/ml)<\/p>\n<\/td>\n<\/tr>\n |
\n| \n Noradrenalina plasm\u00e1tica<\/p>\n<\/td>\n | \n 1019 (VR: 70-700 pg\/ml)<\/p>\n<\/td>\n<\/tr>\n |
\n| \n \u00c1cido vainill\u00edn mand\u00e9lico urinario (Orina 24 h)<\/p>\n<\/td>\n | \n 28,9 (VR: 2,3-5,1 mg\/24 h)<\/p>\n<\/td>\n<\/tr>\n |
\n| \n Adrenalina (Orina 24 h)<\/p>\n<\/td>\n | \n 53,8 (VR: 0,9-20 ug\/24 h)<\/p>\n<\/td>\n<\/tr>\n |
\n| \n Noradrenalina (Orina 24 h)<\/p>\n<\/td>\n | \n 2586 ug\/24 h (VR: 15-80 ug\/24 h)<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=\u00bbon|phone\u00bb _builder_version=\u00bb4.16″ background_color=\u00bb#ffffff\u00bb max_width=\u00bb1280px\u00bb custom_padding=\u00bb12px|40px|12px|40px|true|false\u00bb custom_padding_tablet=\u00bb\u00bb custom_padding_phone=\u00bb|20px||20px||true\u00bb animation_style=\u00bbzoom\u00bb animation_intensity_zoom=\u00bb2%\u00bb border_radii=\u00bbon|12px|12px|12px|12px\u00bb box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb50px\u00bb box_shadow_blur=\u00bb80px\u00bb box_shadow_color=\u00bbrgba(15,19,25,0.1)\u00bb use_custom_width=\u00bbon\u00bb custom_width_px=\u00bb1280px\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.16″ custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n Figura 1: Fondo de ojo<\/strong><\/p>\n[\/et_pb_text][et_pb_image src=\u00bbhttps:\/\/villavicencio.org.ar\/anuario\/wp-content\/uploads\/2026\/02\/Feocromocitoma1.jpg\u00bb title_text=\u00bbFeocromocitoma\u00bb align=\u00bbcenter\u00bb _builder_version=\u00bb4.27.5″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_image][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n Ojo derecho: exudados y hemorragias de 4 cuadrantes, desprendimiento exudativo macular extenso.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=\u00bbon|phone\u00bb _builder_version=\u00bb4.16″ background_color=\u00bb#ffffff\u00bb max_width=\u00bb1280px\u00bb custom_padding=\u00bb14px|40px|14px|40px|true|false\u00bb custom_padding_tablet=\u00bb\u00bb custom_padding_phone=\u00bb|20px||20px||true\u00bb animation_style=\u00bbzoom\u00bb animation_intensity_zoom=\u00bb2%\u00bb border_radii=\u00bbon|12px|12px|12px|12px\u00bb box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb50px\u00bb box_shadow_blur=\u00bb80px\u00bb box_shadow_color=\u00bbrgba(15,19,25,0.1)\u00bb use_custom_width=\u00bbon\u00bb custom_width_px=\u00bb1280px\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.16″ custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n Figura 2: Electrocardiograma<\/strong><\/p>\n[\/et_pb_text][et_pb_image src=\u00bbhttps:\/\/villavicencio.org.ar\/anuario\/wp-content\/uploads\/2026\/02\/Feocromocitoma2.jpg\u00bb title_text=\u00bbFeocromocitoma\u00bb align=\u00bbcenter\u00bb _builder_version=\u00bb4.27.5″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_image][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n Taquicardia sinusal. Signos de hipertrofia ventricular izquierda.
<\/strong><\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=\u00bbon|phone\u00bb _builder_version=\u00bb4.16″ background_color=\u00bb#ffffff\u00bb max_width=\u00bb1280px\u00bb custom_padding=\u00bb12px|40px|12px|40px|true|false\u00bb custom_padding_tablet=\u00bb\u00bb custom_padding_phone=\u00bb|20px||20px||true\u00bb animation_style=\u00bbzoom\u00bb animation_intensity_zoom=\u00bb2%\u00bb border_radii=\u00bbon|12px|12px|12px|12px\u00bb box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb50px\u00bb box_shadow_blur=\u00bb80px\u00bb box_shadow_color=\u00bbrgba(15,19,25,0.1)\u00bb use_custom_width=\u00bbon\u00bb custom_width_px=\u00bb1280px\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.16″ custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n Figura 3: Tomograf\u00eda de abdomen y pelvis con contraste<\/strong><\/p>\n[\/et_pb_text][et_pb_image src=\u00bbhttps:\/\/villavicencio.org.ar\/anuario\/wp-content\/uploads\/2026\/02\/Feocromocitoma3.jpg\u00bb title_text=\u00bbFeocromocitoma\u00bb align=\u00bbcenter\u00bb _builder_version=\u00bb4.27.5″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_image][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n Masa ocupante de espacio suprarrenal izquierdo de 48 x 38 mm de paredes gruesas con centro hipodenso en probable relaci\u00f3n a feocromocitoma.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=\u00bbon|phone\u00bb _builder_version=\u00bb4.16″ background_color=\u00bb#ffffff\u00bb max_width=\u00bb1280px\u00bb custom_padding=\u00bb12px|40px|12px|40px|true|false\u00bb custom_padding_tablet=\u00bb\u00bb custom_padding_phone=\u00bb|20px||20px||true\u00bb animation_style=\u00bbzoom\u00bb animation_intensity_zoom=\u00bb2%\u00bb border_radii=\u00bbon|12px|12px|12px|12px\u00bb box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb50px\u00bb box_shadow_blur=\u00bb80px\u00bb box_shadow_color=\u00bbrgba(15,19,25,0.1)\u00bb use_custom_width=\u00bbon\u00bb custom_width_px=\u00bb1280px\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.16″ custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n Figura 4: Biopsia<\/strong><\/p>\n[\/et_pb_text][et_pb_image src=\u00bbhttps:\/\/villavicencio.org.ar\/anuario\/wp-content\/uploads\/2026\/02\/Feocromocitoma4.jpg\u00bb title_text=\u00bbFeocromocitoma\u00bb align=\u00bbcenter\u00bb _builder_version=\u00bb4.27.5″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_image][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n Pieza quir\u00fargica de adrenalectom\u00eda izquierda videolaparosc\u00f3pica<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding_last_edited=\u00bbon|phone\u00bb _builder_version=\u00bb4.16″ background_color=\u00bb#ffffff\u00bb max_width=\u00bb1280px\u00bb custom_padding=\u00bb12px|40px|12px|40px|true|false\u00bb custom_padding_tablet=\u00bb\u00bb custom_padding_phone=\u00bb|20px||20px||true\u00bb animation_style=\u00bbzoom\u00bb animation_intensity_zoom=\u00bb2%\u00bb border_radii=\u00bbon|12px|12px|12px|12px\u00bb box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb50px\u00bb box_shadow_blur=\u00bb80px\u00bb box_shadow_color=\u00bbrgba(15,19,25,0.1)\u00bb use_custom_width=\u00bbon\u00bb custom_width_px=\u00bb1280px\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.16″ custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n Figura 5: Examen f\u00edsico<\/strong><\/p>\n[\/et_pb_text][et_pb_image src=\u00bbhttps:\/\/villavicencio.org.ar\/anuario\/wp-content\/uploads\/2026\/02\/Feocromocitoma5.jpg\u00bb title_text=\u00bbFeocromocitoma\u00bb align=\u00bbcenter\u00bb _builder_version=\u00bb4.27.5″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_image][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n Manchas color caf\u00e9 con leche.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00bb1″ admin_label=\u00bbCourses\u00bb _builder_version=\u00bb4.16″ custom_padding=\u00bb1px|0px|62px|0px|false|false\u00bb collapsed=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_row custom_padding_last_edited=\u00bbon|phone\u00bb _builder_version=\u00bb4.27.5″ background_color=\u00bb#ffffff\u00bb max_width=\u00bb1280px\u00bb custom_padding=\u00bb12px|40px|12px|40px|true|false\u00bb custom_padding_tablet=\u00bb\u00bb custom_padding_phone=\u00bb|20px||20px||true\u00bb animation_style=\u00bbzoom\u00bb animation_intensity_zoom=\u00bb2%\u00bb border_radii=\u00bbon|12px|12px|12px|12px\u00bb box_shadow_style=\u00bbpreset1″ box_shadow_vertical=\u00bb50px\u00bb box_shadow_blur=\u00bb80px\u00bb box_shadow_color=\u00bbrgba(15,19,25,0.1)\u00bb use_custom_width=\u00bbon\u00bb custom_width_px=\u00bb1280px\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.16″ custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text _builder_version=\u00bb4.27.5″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb12px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb] 1.\tNeumann HPH, Young WF Jr, Eng C. Pheochromocytoma and paraganglioma. N Engl J Med. 2019;381:552-565. Disponible en: https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMra1806651.
\n 2.\tAquieri A, Rodr\u00edguez P, Vissani S, y col. Consenso Argentino de hipertensi\u00f3n arterial. Rev Argent Cardiol. 2025;93:1-70. Disponible en: https:\/\/www.sac.org.ar\/wp-content\/uploads\/2025\/08\/COMPLETO-E-41.pdf.
\n 3.\tOllero Garc\u00eda-Agull\u00f3 D, Iriarte Beroiz A, Rojo Alvaro J, y col. Feocromocitoma familiar asociado a neurofibromatosis tipo 1. Endocrinol Nutr. 2013;60:421-422. Disponible en: 10.1016\/j.endonu.2012.08.004.
\n 4.\tLammert M, Friedman JM, Kluwe L, et al. Prevalence of neurofibromatosis 1 in German children at elementary school enrollment. Arch Dermatol. 2005;141:71-4. Disponible en: 10.1001\/archderm.141.1.71.
\n 5.\tGuijarro De Armas MG, Pavon I, D\u00edaz P, y col. Feocromocitoma adrenal y neurofibromatosis tipo 1. Semergen. 2010;36:480-483. Disponible en: https:\/\/www.elsevier.es\/es-revista-medicina-familia-semergen-40-articulo-feocromocitoma-adrenal-neurofibromatosis-tipo-1-S1138359310001401.
\n6.\tAraujo-Castro M, Pascual-Corrales E, Ortiz-Flores A, y col. Protocolo diagn\u00f3stico ante la sospecha de feocromocitoma. Medicine. 2024;14:750-753. Disponible en: https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0304541224001756.
\n 7.\tOleaga A, Go\u00f1i F. Feocromocitoma: actualizaci\u00f3n diagn\u00f3stica y terap\u00e9utica. Endocrinol Nutr. 2008;55:202-216. Disponible en: https:\/\/www.elsevier.es\/es-revista-endocrinologia-nutricion-12-articulo-feocromocitoma-actualizacion-diagnostica-terapeutica-S1575092208706697.[\/et_pb_text][et_pb_text _builder_version=\u00bb4.24.2″ text_font=\u00bb||||||||\u00bb text_font_size=\u00bb15px\u00bb text_line_height=\u00bb2em\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bb||||||||\u00bb header_3_font=\u00bbEB Garamond||||||||\u00bb header_3_font_size=\u00bb24px\u00bb header_3_line_height=\u00bb1.4em\u00bb header_4_font=\u00bb|700||on|||||\u00bb header_4_text_color=\u00bb#ffdaa4″ header_4_font_size=\u00bb12px\u00bb header_4_letter_spacing=\u00bb2px\u00bb header_4_line_height=\u00bb2em\u00bb text_line_height_tablet=\u00bb\u00bb text_line_height_phone=\u00bb1.6em\u00bb text_line_height_last_edited=\u00bbon|phone\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" El feocromocitoma es un tumor que deriva de las c\u00e9lulas cromafines del sistema nervioso simp\u00e1tico, que produce, almacena, etaboliza y libera catecolaminas y sus metabolitos. El 80-85 % se localiza en la m\u00e9dula adrenal mientras que el 10-15 % restante deriva de tejido cromaf\u00edn extra-adrenal denomin\u00e1ndose paraganglioma.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[47,49],"tags":[48],"class_list":["post-2164","post","type-post","status-publish","format-standard","hentry","category-47","category-a33-presentacion-de-casos-clinicos","tag-anuario-33-2025"],"_links":{"self":[{"href":"https:\/\/villavicencio.org.ar\/anuario\/wp-json\/wp\/v2\/posts\/2164","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/villavicencio.org.ar\/anuario\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/villavicencio.org.ar\/anuario\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/villavicencio.org.ar\/anuario\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/villavicencio.org.ar\/anuario\/wp-json\/wp\/v2\/comments?post=2164"}],"version-history":[{"count":11,"href":"https:\/\/villavicencio.org.ar\/anuario\/wp-json\/wp\/v2\/posts\/2164\/revisions"}],"predecessor-version":[{"id":2196,"href":"https:\/\/villavicencio.org.ar\/anuario\/wp-json\/wp\/v2\/posts\/2164\/revisions\/2196"}],"wp:attachment":[{"href":"https:\/\/villavicencio.org.ar\/anuario\/wp-json\/wp\/v2\/media?parent=2164"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/villavicencio.org.ar\/anuario\/wp-json\/wp\/v2\/categories?post=2164"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/villavicencio.org.ar\/anuario\/wp-json\/wp\/v2\/tags?post=2164"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}} |